Corticosteroids in advanced cancer.

Corticosteroids in advanced cancer.

Despite the fact that there are only a few controlled trials demonstrating the benefits associated with the use of corticosteroids in specific situations, these agents are administered frequently to patients with advanced cancer. Corticosteroids may be used alone or as adjuvants in combination with other palliative or antineoplastic treatments. For example, corticosteroids may help prevent naus...

Response of paraneoplastic nephrotic syndrome to corticosteroids combined with chemotherapy for advanced lung cancer: a case report and literature review

Paraneoplastic nephrotic syndrome is a rare manifestation associated with various malignancies, the most common of which is lung cancer. In practice, no reports have yet supported the notion that corticosteroids combined with cancer therapy for the syndrome would confer a benefit. We describe a female patient in whom advanced lung cancer associated with membranous nephropathy reached partial re...

Corticosteroids and peptic ulceration prophylaxis in patients with advanced cancer.

Corticosteroids for the resolution of malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer.

BACKGROUND Gastrointestinal and ovarian cancers are common cancers. The incidence of associated malignant bowel obstruction in patients with advanced cancers of these types is not known, and the best management of these patients is controversial. Inappropriate management may result in uncontrolled (faeculant) vomiting, pain and distress. Management of the symptoms can include palliative surgery...

Predictors of Delirium in Corticosteroid-Treated Patients with Advanced Cancer: An Exploratory, Multicenter, Prospective, Observational Study.

BACKGROUND Corticosteroids are often used to treat fatigue and anorexia, but occasionally produce delirium. Information on the predictors of delirium in corticosteroid-treated cancer patients remains limited. OBJECTIVE To identify potential factors predicting the development of delirium in corticosteroid-treated cancer patients. DESIGN An exploratory, multicenter, prospective, observational...

Malignant ureteric obstruction relieved by dexamethasone.

A case is described where dexamethasone relieved tumour-induced ureteric obstruction with improvement in the biochemical abnormalities and clinical features of post-renal failure. Such intervention is not always appropriate but may be of great value in symptom control. Because of this and similar applications, corticosteroids are finding increasing favour in the palliative care of patients with...